Journal: Neurobiology of Stress

Article Title: Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress

doi: 10.1016/j.ynstr.2022.100437

Figure Lengend Snippet: Pre-stress: Basal social interaction and corticosterone levels did not predict resilience or susceptibility post social defeat. 2 A. Schematic timeline of pre-post SI test and AM/PM corticosterone (CORT) sampling. 2 B. In control mice, SI Ratios displayed before the rotation did not correlate with SI ratios measured after the rotation. 2C. In defeated mice, SI ratios measured before defeat did not correlate with SI ratios displayed after defeat. 2D. CORT ELISA showing diurnal patterns of CORT before and after CSDS/CR. For all groups, the diurnal CORT patterns remained stable throughout the experiment, with higher PM CORT. For either pre- or post-CSDS/CR timepoints, there were no differences in CORT levels between groups. Significance Codes: n.s. = not significant. Colors: grey = control, blue = resilient, yellow = susceptible.

Article Snippet: Plasma was then stored at −80 °C until used for CORT analysis with the Arbor Assays CORT ELISA kit (Cat#K014–H1). (Assessed in Cohort 1).

Techniques: Sampling, Control, Enzyme-linked Immunosorbent Assay